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In vitro cytotoxicity and transfection efficiency of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate nanoparticles

Purpose: The objective of this work was to formulate a delivery system of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate (CS-DS) nanoparticles, and to evaluate their influence on in vitro cytotoxicity and transfection efficiency of p53 gene. Methods: The prepared pDNA-loaded CS-DS nanopar...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Hashem, Fahima M, Nasr, Mohamed, Khairy, Ahmed, Alqurshi, Abdulmalik
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557187/
https://ncbi.nlm.nih.gov/pubmed/31239671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S205324
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