Expanding the CITE-seq tool-kit: Detection of proteins, transcriptomes, clonotypes and CRISPR perturbations with multiplexing, in a single assay

Multi-modal single-cell assays provide high-resolution snapshots of complex cell populations but are mostly limited to transcriptome plus an additional modality. Here, we describe Expanded CRISPR-compatible Cellular Indexing of Transcriptomes and Epitopes by sequencing (ECCITE-seq) for the high-thro...

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Publicado no:Nat Methods
Main Authors: Mimitou, Eleni P., Cheng, Anthony, Montalbano, Antonino, Hao, Stephanie, Stoeckius, Marlon, Legut, Mateusz, Roush, Timothy, Herrera, Alberto, Papalexi, Efthymia, Ouyang, Zhengquing, Satija, Rahul, Sanjana, Neville E., Koralov, Sergei B, Smibert, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557128/
https://ncbi.nlm.nih.gov/pubmed/31011186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0392-0
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