Expanding the CITE-seq tool-kit: Detection of proteins, transcriptomes, clonotypes and CRISPR perturbations with multiplexing, in a single assay

Multi-modal single-cell assays provide high-resolution snapshots of complex cell populations but are mostly limited to transcriptome plus an additional modality. Here, we describe Expanded CRISPR-compatible Cellular Indexing of Transcriptomes and Epitopes by sequencing (ECCITE-seq) for the high-thro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Methods
Prif Awduron: Mimitou, Eleni P., Cheng, Anthony, Montalbano, Antonino, Hao, Stephanie, Stoeckius, Marlon, Legut, Mateusz, Roush, Timothy, Herrera, Alberto, Papalexi, Efthymia, Ouyang, Zhengquing, Satija, Rahul, Sanjana, Neville E., Koralov, Sergei B, Smibert, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557128/
https://ncbi.nlm.nih.gov/pubmed/31011186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0392-0
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