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Analysis of transgenic zebrafish expressing the Lenz-Majewski syndrome gene PTDSS1 in skeletal cell lineages

Background: Lenz-Majewski syndrome (LMS) is characterized by osteosclerosis and hyperostosis of skull, vertebrae and tubular bones as well as craniofacial, dental, cutaneous, and digit abnormalities. We previously found that LMS is caused by de novo dominant missense mutations in the  PTDSS1 gene, w...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Seda, Marian, Peskett, Emma, Demetriou, Charalambos, Bryant, Dale, Moore, Gudrun E., Stanier, Philip, Jenkins, Dagan
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557000/
https://ncbi.nlm.nih.gov/pubmed/31231513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.17314.1
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