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Cell-Type Heterogeneity in Adipose Tissue Is Associated with Complex Traits and Reveals Disease-Relevant Cell-Specific eQTLs

Adipose tissue is an important endocrine organ with a role in many cardiometabolic diseases. It is comprised of a heterogeneous collection of cell types that can differentially impact disease phenotypes. Cellular heterogeneity can also confound -omic analyses but is rarely taken into account in anal...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Glastonbury, Craig A., Couto Alves, Alexessander, El-Sayed Moustafa, Julia S., Small, Kerrin S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556877/
https://ncbi.nlm.nih.gov/pubmed/31130283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.03.025
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