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Loss of ZNF587B and SULF1 contributed to cisplatin resistance in ovarian cancer cell lines based on Genome-scale CRISPR/Cas9 screening

Ovarian cancer is one of the most lethal malignancies of the female reproductive system. Platinum-resistance is the major obstacle in the successful treatment of ovarian cancer. Previous studies largely failed to identify the key genes associated with platinum-resistance by using candidate genes tes...

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Dettagli Bibliografici
Pubblicato in:Am J Cancer Res
Autori principali: Ouyang, Qianying, Liu, Yujie, Tan, Jieqiong, Li, Jie, Yang, Dawei, Zeng, Feiyue, Huang, Weihua, Kong, Yi, Liu, Zhaoqian, Zhou, Honghao, Liu, Yingzi
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556596/
https://ncbi.nlm.nih.gov/pubmed/31218106
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