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Chemical suppression of specific C-C chemokine signaling pathways enhances cardiac reprogramming
Reprogramming of fibroblasts into induced cardiomyocytes (iCMs) is a potentially promising strategy for regenerating a damaged heart. However, low fibroblast–cardiomyocyte conversion rates remain a major challenge in this reprogramming. To this end, here we conducted a chemical screen and identified...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6556576/ https://ncbi.nlm.nih.gov/pubmed/31023824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006000 |
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