CD45RA(+)CCR7(−) CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab

BACKGROUND: Checkpoint inhibitors have become standard care of treatment for non-small cell lung cancer (NSCLC), yet only a limited fraction of patients experiences durable clinical benefit, highlighting the need for markers to stratify patient populations. METHODS: To prospectively identify patient...

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Bibliografische gegevens
Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Kunert, Andre, Basak, Edwin A., Hurkmans, Daan P., Balcioglu, Hayri E., Klaver, Yarne, van Brakel, Mandy, Oostvogels, Astrid A. M., Lamers, Cor H. J., Bins, Sander, Koolen, Stijn L. W., van der Veldt, Astrid A. M., Sleijfer, Stefan, Mathijssen, Ron H. J., Aerts, Joachim G. J. V., Debets, Reno
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555948/
https://ncbi.nlm.nih.gov/pubmed/31176366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0608-y
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