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Analgesic transient receptor potential vanilloid‐1‐active compounds inhibit native and recombinant T‐type calcium channels

BACKGROUND AND PURPOSE: T‐type calcium (Ca(v)3) and transient receptor potential vanilloid‐1 (TRPV1) channels play central roles in the control of excitability in the peripheral nervous system and are regarded as potential therapeutic pain targets. Modulators that either activate or inhibit TRPV1‐me...

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Vydáno v:Br J Pharmacol
Hlavní autoři: McArthur, Jeffrey R., Finol‐Urdaneta, Rocio K., Adams, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555866/
https://ncbi.nlm.nih.gov/pubmed/30927254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14676
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