Conotoxins Targeting Neuronal Voltage-Gated Sodium Channel Subtypes: Potential Analgesics?

Voltage-gated sodium channels (VGSC) are the primary mediators of electrical signal amplification and propagation in excitable cells. VGSC subtypes are diverse, with different biophysical and pharmacological properties, and varied tissue distribution. Altered VGSC expression and/or increased VGSC ac...

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Detalles Bibliográficos
Autores principales: Knapp, Oliver, McArthur, Jeffrey R., Adams, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509706/
https://ncbi.nlm.nih.gov/pubmed/23202314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins4111236
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