Iron Catalysis of Lipid Peroxidation in Ferroptosis: Regulated Enzymatic or Random Free Radical Reaction?

Duality of iron as an essential cofactor of many enzymatic metabolic processes and as a catalyst of poorly controlled redox-cycling reactions defines its possible biological beneficial and hazardous role in the body. In this review, we discuss these two “faces” of iron in a newly conceptualized prog...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Stoyanovsky, DA, Tyurina, YY, Shrivastava, I, Bahar, I., Tyurin, VA, Protchenko, O, Jadhav, S, Bolevich, SB, Kozlov, AV, Vladimirov, YA, Shvedova, AA, Philpott, CC., Bayir, H., Kagan, VE
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555767/
https://ncbi.nlm.nih.gov/pubmed/30217775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2018.09.008
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