The natural product elegaphenone potentiates antibiotic effects against Pseudomonas aeruginosa

Natural products represent a rich source for antibiotics addressing versatile cellular targets. The deconvolution of their targets via chemical proteomics is often challenged by the introduction of large photocrosslinkers. Here we select elegaphenone, a largely uncharacterized natural product antibi...

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Publicado en:Angew Chem Int Ed Engl
Autores principales: Zhao, Weining, Cross, Ashley R., Crowe-McAuliffe, Caillan, Weigert-Munoz, Angela, Csatary, Erika E., Solinski, Amy E., Krysiak, Joanna, Goldberg, Joanna B., Wilson, Daniel N., Medina, Eva, Wuest, William M., Sieber, Stephan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555641/
https://ncbi.nlm.nih.gov/pubmed/30969469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201903472
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