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A new heparan sulfate from the mollusk Nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of Plasmodium falciparum
BACKGROUND: Despite treatment with effective antimalarial drugs, the mortality rate is still high in severe cases of the disease, highlighting the need to find adjunct therapies that can inhibit the adhesion of Plasmodium falciparum-infected erythrocytes (Pf-iEs). OBJECTIVES: In this context, we eva...
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| Publicado no: | Mem Inst Oswaldo Cruz |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Instituto Oswaldo Cruz, Ministério da Saúde
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6555591/ https://ncbi.nlm.nih.gov/pubmed/31188952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760190088 |
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