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Upregulation of sphingosine-1-phosphate receptor 3 on fibroblast-like synoviocytes is associated with the development of collagen-induced arthritis via increased interleukin-6 production
BACKGROUND: Sphingosine-1-phosphate receptor 3 (S1P(3)) is one of five receptors for sphingosine-1-phosphate (S1P). S1P/S1P(3) signaling is involved in numerous physiological and pathological processes including bone metabolism, sepsis, cancer, and immunity. In rheumatoid arthritis (RA), fibroblast-...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | PLoS One |
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| Prif Awduron: | , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Public Library of Science
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6555509/ https://ncbi.nlm.nih.gov/pubmed/31173610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218090 |
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