Tumor-secreted PAI-1 promotes breast cancer metastasis via the induction of adipocyte-derived collagen remodeling

BACKGROUND: Breast cancer cells recruit surrounding stromal cells, such as cancer-associated fibroblasts (CAFs), to remodel collagen and promote tumor metastasis. Adipocytes are the most abundant stromal partners in breast tissue, local invasion of breast cancer leads to the proximity of cancer cell...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Commun Signal
Auteurs principaux: Wei, Xiaohui, Li, Sijing, He, Jinyong, Du, Hongzhi, Liu, Yang, Yu, Wei, Hu, Haolin, Han, Lifei, Wang, Chenfei, Li, Hongyang, Shi, Xin, Zhan, Meixiao, Lu, Ligong, Yuan, Shengtao, Sun, Li
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554964/
https://ncbi.nlm.nih.gov/pubmed/31170987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0373-z
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires