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OR30-5 Germline Ablation of G-Protein Subunit Alpha-11 in Mice Causes Hypercalcemia That Is Rectified by Treatment with Cinacalcet

G-protein subunit α-(11) (Gα(11)) is a signalling partner of the calcium-sensing receptor (CaSR), which is a G-protein coupled receptor that plays a major role in calcium homeostasis by regulating parathyroid hormone (PTH) secretion, urinary calcium excretion and skeletal development. Although loss-...

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Dades bibliogràfiques
Publicat a:J Endocr Soc
Autors principals: Hannan, Fadil, Olesen, Mie, Hough, Tertius, Stewart, Michelle, Wells, Sara, Thakker, Rajesh
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554764/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR30-5
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