Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice

Osteoarthritis (OA), a common degenerative joint disease, is principally characterized by inflammation and destruction of cartilage. Nobiletin, an extract of the peel of citrus fruits, is known to have anti-inflammatory properties. However, the mechanisms by which nobiletin plays a protective role i...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lin, Zeng, Wu, Dengying, Huang, Lipeng, Jiang, Chao, Pan, Tianlong, Kang, Xiaodiao, Pan, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554687/
https://ncbi.nlm.nih.gov/pubmed/31214026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00570
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