The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of G(α) and G(βγ) Subunits

The discovery of a G-protein-coupled receptor for lactate named hydroxycarboxylic acid receptor 1 (HCAR1) in neurons has pointed to additional nonmetabolic effects of lactate for regulating neuronal network activity. In this study, we characterized the intracellular pathways engaged by HCAR1 activat...

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Veröffentlicht in:J Neurosci
Hauptverfasser: de Castro Abrantes, Haíssa, Briquet, Marc, Schmuziger, Céline, Restivo, Leonardo, Puyal, Julien, Rosenberg, Nadia, Rocher, Anne-Bérengère, Offermanns, Stefan, Chatton, Jean-Yves
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2019
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554634/
https://ncbi.nlm.nih.gov/pubmed/30926749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2092-18.2019
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