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GDP-Mannose Pyrophosphorylase: A Biologically Validated Target for Drug Development Against Leishmaniasis

Leishmaniases are neglected tropical diseases that threaten about 350 million people in 98 countries around the world. In order to find new antileishmanial drugs, an original approach consists in reducing the pathogenic effect of the parasite by impairing the glycoconjugate biosynthesis, necessary f...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Pomel, Sébastien, Mao, Wei, Ha-Duong, Tâp, Cavé, Christian, Loiseau, Philippe M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554559/
https://ncbi.nlm.nih.gov/pubmed/31214516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00186
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