GDP-Mannose Pyrophosphorylase: A Biologically Validated Target for Drug Development Against Leishmaniasis

Leishmaniases are neglected tropical diseases that threaten about 350 million people in 98 countries around the world. In order to find new antileishmanial drugs, an original approach consists in reducing the pathogenic effect of the parasite by impairing the glycoconjugate biosynthesis, necessary f...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Pomel, Sébastien, Mao, Wei, Ha-Duong, Tâp, Cavé, Christian, Loiseau, Philippe M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554559/
https://ncbi.nlm.nih.gov/pubmed/31214516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00186
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