In silico analysis of a therapeutic target in Leishmania infantum: the guanosine-diphospho-D-mannose pyrophosphorylase

Leishmaniases are tropical and sub-tropical diseases for which classical drugs (i.e. antimonials) exhibit toxicity and drug resistance. Such a situation requires to find new chemical series with antileishmanial activity. This work consists in analyzing the structure of a validated target in Leishman...

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Hlavní autoři: Pomel, S., Rodrigo, J., Hendra, F., Cavé, C., Loiseau, P.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: EDP Sciences 2012
Témata:
Original Contribution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671423/
https://ncbi.nlm.nih.gov/pubmed/22314241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/parasite/2012191063
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