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Solution Structure of C. elegans UNC-6: A Nematode Paralogue of the Axon Guidance Protein Netrin-1

UNCoordinated-6 (UNC-6) was the first member of the netrin family to be discovered in Caenorhabditis elegans. With homology to human netrin-1, it is a key signaling molecule involved in directing axon migration in nematodes. Similar to netrin-1, UNC-6 interacts with multiple receptors (UNC-5 and UNC...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Krahn, Natalie, Meier, Markus, Reuten, Raphael, Koch, Manuel, Stetefeld, Joerg, Patel, Trushar R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554493/
https://ncbi.nlm.nih.gov/pubmed/31103237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.04.033
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