The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood–testis barrier and results in hypospermatogenesis

Non-obstructive azoospermia (NOA) severely affects male infertility, however, the deep mechanisms of this disease are rarely interpreted. In this study, we find that undifferentiated spermatogonial stem cells (SSCs) still exist in the basal compartment of the seminiferous tubules and the blood–testi...

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Publicat a:Cell Death Dis
Autors principals: Zhu, Ruilou, Wang, Jiangnan, Feng, Tianxiang, Hu, Xuechun, Jiang, Chen, Wang, Xiuxing, Li, Kang, Sang, Yongjuan, Hua, Yue, Sun, Haixiang, Yao, Bing, Li, Chaojun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554403/
https://ncbi.nlm.nih.gov/pubmed/31171774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1688-9
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