Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate

Mevalonate kinase (MVK) mutations were previously identified in disseminated superficial actinic porokeratosis. However, the role of MVK in differentiation, apoptosis and prenylation of keratinocytes requires further investigation. Farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP)...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Li, Min, Min, Wei, Wang, Jianbo, Wang, Lu, Li, Yan, Zhou, Naihui, Yang, Ziliang, Qian, Qihong
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086283/
https://ncbi.nlm.nih.gov/pubmed/32256770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8569
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