Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies

Genetic factors underlying leukocyte telomere length (LTL) may provide insights into telomere homeostasis, with direct links to disease susceptibility. Genetic evaluation of 23,096 Singaporean Chinese samples identifies 10 genome-wide loci (P < 5 × 10(−8)). Several of these contain candidate gene...

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Vydáno v:Nat Commun
Hlavní autoři: Dorajoo, Rajkumar, Chang, Xuling, Gurung, Resham Lal, Li, Zheng, Wang, Ling, Wang, Renwei, Beckman, Kenneth B., Adams-Haduch, Jennifer, M, Yiamunaa, Liu, Sylvia, Meah, Wee Yang, Sim, Kar Seng, Lim, Su Chi, Friedlander, Yechiel, Liu, Jianjun, van Dam, Rob M., Yuan, Jian-Min, Koh, Woon-Puay, Khor, Chiea Chuen, Heng, Chew-Kiat
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554354/
https://ncbi.nlm.nih.gov/pubmed/31171785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10443-2
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