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Interaction effects between Paraoxonase 1 variants and cigarette smoking on risk of coronary heart disease in a Singaporean Chinese population

OBJECTIVE: Paraoxonase 1 (PON1) plays an important role in reducing the risk of coronary heart disease (CHD). Smoking is known to reduce PON1 activity. We aimed to investigate the effects of interactions between PON1 variants and smoking on CHD in the Singaporean Chinese population. METHODS: In a ca...

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Bibliographic Details
Published in:Atherosclerosis
Main Authors: Han, Yi, Dorajoo, Rajkumar, Ke, Tingjing, Ayala, Burger, Chang, Xuling, Khor, Chiea-Chuen, van Dam, Rob M., Yuan, Jian-Min, Koh, Woon-Puay, Liu, Jianjun, Goh, Daniel Y.T., Friedlander, Yechiel, Heng, Chew-Kiat
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501379/
https://ncbi.nlm.nih.gov/pubmed/25746376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.01.042
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