Aβ oligomers promote oligodendrocyte differentiation and maturation via integrin β1 and Fyn kinase signaling

Alzheimer´s disease (AD) is characterized by a progressive cognitive decline that correlates with the levels of amyloid β-peptide (Aβ) oligomers. Strong evidences connect changes of oligodendrocyte function with the onset of neurodegeneration in AD. However, the mechanisms controlling oligodendrocyt...

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Vydáno v:Cell Death Dis
Hlavní autoři: Quintela-López, Tania, Ortiz-Sanz, Carolina, Serrano-Regal, Mari Paz, Gaminde-Blasco, Adhara, Valero, Jorge, Baleriola, Jimena, Sánchez-Gómez, Maria Victoria, Matute, Carlos, Alberdi, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554322/
https://ncbi.nlm.nih.gov/pubmed/31171765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1636-8
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