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A Crosstalk Between Brain Cholesterol Oxidation and Glucose Metabolism in Alzheimer’s Disease

In Alzheimer’s disease (AD), both cholesterol and glucose dysmetabolism precede the onset of memory deficit and contribute to the disease’s progression. It is indeed now believed that oxidized cholesterol in the form of oxysterols and altered glucose uptake are the main triggers in AD affecting prod...

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Pubblicato in:Front Neurosci
Autori principali: Gamba, Paola, Staurenghi, Erica, Testa, Gabriella, Giannelli, Serena, Sottero, Barbara, Leonarduzzi, Gabriella
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554318/
https://ncbi.nlm.nih.gov/pubmed/31213973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00556
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