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A Crosstalk Between Brain Cholesterol Oxidation and Glucose Metabolism in Alzheimer’s Disease

In Alzheimer’s disease (AD), both cholesterol and glucose dysmetabolism precede the onset of memory deficit and contribute to the disease’s progression. It is indeed now believed that oxidized cholesterol in the form of oxysterols and altered glucose uptake are the main triggers in AD affecting prod...

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Vydáno v:Front Neurosci
Hlavní autoři: Gamba, Paola, Staurenghi, Erica, Testa, Gabriella, Giannelli, Serena, Sottero, Barbara, Leonarduzzi, Gabriella
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554318/
https://ncbi.nlm.nih.gov/pubmed/31213973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00556
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