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Raltitrexed (Tomudex) administration in patients with relapsed metastatic colorectal cancer after weekly irinotecan/5-Fluorouracil/Leucovorin chemotherapy

PURPOSE: The present study aimed at evaluating the efficacy of Raltitrexed, a specific thymidilate synthase inhibitor, in patients with advanced colorectal cancer (ACC) in relapse (>8 weeks) after a prior response or disease stabilization to first-line chemotherapy combination with lrinotecan+5-F...

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Autors principals: Tsavaris, Nicolas, Kosmas, Christos, Vadiaka, Maria, Koufos, Christos
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC65542/
https://ncbi.nlm.nih.gov/pubmed/11860608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-2-2
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