Neoplasm Risk Among Individuals With a Pathogenic Germline Variant in DICER1

PURPOSE: DICER1 syndrome is an autosomal-dominant, pleiotropic tumor-predisposition disorder caused by pathogenic germline variants in DICER1. We sought to quantify risk, hazard rates, and the probability of neoplasm incidence accounting for competing risks (“cumulative incidence”) of neoplasms (ben...

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Pubblicato in:J Clin Oncol
Autori principali: Stewart, Douglas R., Best, Ana F., Williams, Gretchen M., Harney, Laura A., Carr, Ann G., Harris, Anne K., Kratz, Christian P., Dehner, Louis P., Messinger, Yoav H., Rosenberg, Philip S., Hill, D. Ashley, Schultz, Kris Ann P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2019
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ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553836/
https://ncbi.nlm.nih.gov/pubmed/30715996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2018.78.4678
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