Neoplasm Risk Among Individuals With a Pathogenic Germline Variant in DICER1

PURPOSE: DICER1 syndrome is an autosomal-dominant, pleiotropic tumor-predisposition disorder caused by pathogenic germline variants in DICER1. We sought to quantify risk, hazard rates, and the probability of neoplasm incidence accounting for competing risks (“cumulative incidence”) of neoplasms (ben...

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Publicado en:J Clin Oncol
Autores principales: Stewart, Douglas R., Best, Ana F., Williams, Gretchen M., Harney, Laura A., Carr, Ann G., Harris, Anne K., Kratz, Christian P., Dehner, Louis P., Messinger, Yoav H., Rosenberg, Philip S., Hill, D. Ashley, Schultz, Kris Ann P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553836/
https://ncbi.nlm.nih.gov/pubmed/30715996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2018.78.4678
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