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Catalytic Asymmetric Synthesis of α-Arylpyrrolidines and Benzo-fused Nitrogen Heterocycles
Herein we report a practical two-step synthetic route to α-arylpyrrolidines consisting of Suzuki-Miyaura cross-coupling and enantioselective copper-catalyzed intramolecular hydroamination reactions. The excellent stereoselectivity and broad scope for the transformation of substrates with pharmaceuti...
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| Udgivet i: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6553474/ https://ncbi.nlm.nih.gov/pubmed/30659729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201814331 |
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