SUN-042 Loss of the 18-Kda Translocator Protein Tspo Destabilizes Cholesterol Homeostasis in a Hepatic Steatosis Cell Model

The 18-kDa translocator protein TSPO is a conserved ubiquitous high affinity cholesterol binding protein localized in the outer mitochondrial membrane. It plays a critical role in the segregation and transport of free cholesterol (FC) from the outer to the inner mitochondrial membrane in steroidogen...

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Bibliografische gegevens
Gepubliceerd in:J Endocr Soc
Hoofdauteurs: Li, Yuchang, Chen, Liting, Sottas, Chantal, Li, Lu, Papadopoulos, Vassilios
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2019
Onderwerpen:
Genetics and Development (including Gene Regulation)
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553298/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-042
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