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SUN-028 Role of Estrogen Receptor Alpha (ERa) Acetylation in Estrogen-Dependent Gene Regulation in Breast Cancers
Estrogens, such as 17β- estradiol (E2), act through estrogen receptor alpha (ERα), a ligand-regulated transcription factor that binds across the genome to promote enhancer formation and regulate gene expression. ERα is expressed in approximately 70% of breast cancers, where it regulates the transcri...
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| Publicado no: | J Endocr Soc |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6552999/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-028 |
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