SUN-028 Role of Estrogen Receptor Alpha (ERa) Acetylation in Estrogen-Dependent Gene Regulation in Breast Cancers

Estrogens, such as 17β- estradiol (E2), act through estrogen receptor alpha (ERα), a ligand-regulated transcription factor that binds across the genome to promote enhancer formation and regulate gene expression. ERα is expressed in approximately 70% of breast cancers, where it regulates the transcri...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Vasquez, Yasmin, Setlem, Rohit, Murakami, Shino, Kraus, W
Format: Artigo
Language:Inglês
Published: Endocrine Society 2019
Subjects:
Steroid Hormones and Receptors
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552999/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-028
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