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Familial segregation of a 5q15‐q21.2 deletion associated with facial dysmorphism and speech delay

We report a two‐generation family with four females harboring an 8.5Mb heterozygous deletion of 5q15‐q21.2 who present with dysmorphic craniofacial features and speech delay. We hypothesize haploinsufficiency of CHD1 to be contributing to the clinical features observed in this family.

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Case Rep
Main Authors: Zepeda‐Mendoza, Cinthya, Goodenberger, McKinsey L., Kuhl, Ashley, Rice, Gregory M., Hoppman, Nicole
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552940/
https://ncbi.nlm.nih.gov/pubmed/31183085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.2186
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