Caricamento...

Familial segregation of a 5q15‐q21.2 deletion associated with facial dysmorphism and speech delay

We report a two‐generation family with four females harboring an 8.5Mb heterozygous deletion of 5q15‐q21.2 who present with dysmorphic craniofacial features and speech delay. We hypothesize haploinsufficiency of CHD1 to be contributing to the clinical features observed in this family.

Salvato in:
Dettagli Bibliografici
Pubblicato in:Clin Case Rep
Autori principali: Zepeda‐Mendoza, Cinthya, Goodenberger, McKinsey L., Kuhl, Ashley, Rice, Gregory M., Hoppman, Nicole
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552940/
https://ncbi.nlm.nih.gov/pubmed/31183085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.2186
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !