SUN-213 Hsd17b3 Knockout Mice Serve As A Model To Define Mechanisms Behind The Altered Endocrine Phenotype Of Patients With Hsd17b3 Mutations

Hydroxysteroid (17β) dehydrogenase type 3 (HSD17B3) is known to be the primary HSD17B enzyme converting androstenedione (A) to testosterone (T) in human testes, and thus, to be important for sexual maturation in boys and for reproductive health later in life. In particular, inherited HSD17B3 deficie...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Poutanen, Matti, Junnila, Arttu, Zhang, Fu-Ping, Huhtaniemi, Riikka, Strauss, Leena, Kotaja, Noora, Ohlsson, Claes, Huhtaniemi, Ilpo, Sipilä, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Reproductive Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552858/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-213
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