SUN-213 Hsd17b3 Knockout Mice Serve As A Model To Define Mechanisms Behind The Altered Endocrine Phenotype Of Patients With Hsd17b3 Mutations

Hydroxysteroid (17β) dehydrogenase type 3 (HSD17B3) is known to be the primary HSD17B enzyme converting androstenedione (A) to testosterone (T) in human testes, and thus, to be important for sexual maturation in boys and for reproductive health later in life. In particular, inherited HSD17B3 deficie...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Poutanen, Matti, Junnila, Arttu, Zhang, Fu-Ping, Huhtaniemi, Riikka, Strauss, Leena, Kotaja, Noora, Ohlsson, Claes, Huhtaniemi, Ilpo, Sipilä, Petra
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2019
Materias:
Reproductive Endocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552858/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-213
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