SUN-011 Identification Of Regulators Of Estrogenic Signalling In ER-positive Breast Cancer Cells By Whole Genome shRNA Screening

Over 70% of breast tumours express estrogen receptor alpha (ERα), a ligand-inducible transcription factor. Stimulation with estradiol leads to receptor binding to estrogen response elements (EREs) in target genes regulatory sequences in association with transcriptional cofactors. This results in alt...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Kulpa, Justyna, Wang, Xiaofeng, Dianati, Elham, Diennet, Marine, Audemard, Eric, Mader, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Steroid Hormones and Receptors
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552743/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-011
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