SAT-LB035 The G Protein-Coupled Estrogen Receptor GPER Plays a Dominant Role in Human Islet Cell Proliferation upon High Glucose

Estrogen exerts its effects through genomic and rapid extra-nuclear signaling pathways. The classic estrogen receptors, ERα and ERβ have demonstrated favorable effects on beta-cell function and survival but their clinical utility has been questioned owing to oncogenic potential and concerns regardin...

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Bibliografiska uppgifter
I publikationen:J Endocr Soc
Huvudupphovsmän: Shaklai, Sigal, Grafi-Cohen, Meital, Sharon, Orli, Shefer, Gabi, Somjen, Dalia, Stern, Naftali
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2019
Ämnen:
Diabetes Mellitus and Glucose Metabolism
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552641/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-LB035
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