SUN-LB009 Epigenetic Changes in Response to Metabolic Modifiers in Late Life: Exercise, High Fat Diet, and Angiotenin1-7 Effects on Metabolic Health and DNA Methylation in Frail Old Mice

Background: Reduced muscle and bone-mass and quality as well as impaired energy homeostasis are seen in both aging and the metabolic syndrome (MetS). We previously showed that exercise and Angiotensin1-7 (A1-7) ameliorate this burden in young rats, but their effect vis-a-vis aging is unknown. Aims:...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Endocr Soc
المؤلفون الرئيسيون: Shefer, Gabi, Marcus-Perlman, Yonit, Shahal, Tamar, Segev, Elad, Ebenstein, Yuval, Stern, Naftali
التنسيق: Artigo
اللغة:Inglês
منشور في: Endocrine Society 2019
الموضوعات:
Genetics and Development (including Gene Regulation)
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552835/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-LB009
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