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SAT-155 Temporal Activation of the Unfolded Protein Response and Concomitant Downregulation of Key Hepatic Transcription Factors in Critical Illness

Background: Critically ill patients often develop multiple organ failure accompanied by profound metabolic and endocrine alterations. The pathogenesis is incompletely understood, but the development of cellular stress, including endoplasmic reticulum (ER) stress, might play a pivotal role (1). Indee...

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Bibliografski detalji
Izdano u:J Endocr Soc
Glavni autori: Vankrunkelsven, Wouter, Dubois, Vanessa, Derese, Inge, Langouche, Lies, Eeckhoute, Jérôme, Van Den Berghe, Greet, Vanhorebeek, Ilse
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552495/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-155
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