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Synthesis of sterically hindered 4,5-diarylphenanthrenes via acid-catalyzed bisannulation of benzenediacetaldehydes with alkynes

The synthesis of sterically hindered phenanthrenes via acid-catalyzed bisannulation reaction is described. Treatment of 1,4-benzenediacetaldehyde with terminal aryl alkynes in the presence of B(C(6)F(5))(3) provides 4,5-diarylphenanthrenes in good yields with excellent regioselectivity. The use of i...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Li, Yuanming, Yagi, Akiko, Itami, Kenichiro
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552489/
https://ncbi.nlm.nih.gov/pubmed/31293729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00334g
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