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Mass spectrometry–based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots

The roles of factor XIIIa–specific cross-links in thrombus formation, regression, or probability for embolization are largely unknown. A molecular understanding of fibrin architecture at the level of these cross-links could inform the development of therapeutic strategies to prevent the sequelae of...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Schmitt, Lauren R., Henderson, Rachel, Barrett, Alexander, Darula, Zsuzsanna, Issaian, Aaron, D'Alessandro, Angelo, Clendenen, Nathan, Hansen, Kirk C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552431/
https://ncbi.nlm.nih.gov/pubmed/31028172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.007981
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