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The redox regulator sulfiredoxin forms a complex with thioredoxin domain–containing 5 protein in response to ER stress in lung cancer cells

Sulfiredoxin (Srx) reduces hyperoxidized 2-cysteine–containing peroxiredoxins (Prxs) and protects cells against oxidative stress. Previous studies have shown that Srx is highly expressed in primary specimens of lung cancer patients and plays a pivotal role in lung tumorigenesis and cancer progressio...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chawsheen, Hedy A., Jiang, Hong, Ying, Qi, Ding, Na, Thapa, Pratik, Wei, Qiou
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552416/
https://ncbi.nlm.nih.gov/pubmed/31000628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005804
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