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Sulfiredoxin Promotes Colorectal Cancer Cell Invasion and Metastasis through a Novel Mechanism of Enhancing EGFR Signaling()

Sulfiredoxin (SRXN1/Srx) is a multifunction enzyme with a primary antioxidant role of reducing the overoxidized inactive form of peroxiredoxins (Prxs). The function and mechanisms of Srx in cancer development are not well understood. Here, Srx is preferentially expressed in human colorectal cancer (...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Jiang, Hong, Wu, Lisha, Chen, Jing, Mishra, Murli, Chawsheen, Hedy A., Zhu, Haining, Wei, Qiou
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684963/
https://ncbi.nlm.nih.gov/pubmed/26290602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0240
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