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SAT-045 Transient Developmental Hypothyroidism Results in Dysregulation of Neural Progenitors and Birth Defect Formation in Rats

Cortical heterotopias are clusters of ectopic neurons in the brain, and are commonly associated with pharmaceutical resistant epilepsy in patients. We have previously characterized the robust penetrance of a cortical heterotopia in a rat model, induced by thyroid hormone (TH) disruption during gesta...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: O'Shaughnessy, Katherine, Thomas, Susan, Spring, Stephanie, Ford, Jermaine, Ford, Richard, Gilbert, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552232/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-045
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