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SAT-045 Transient Developmental Hypothyroidism Results in Dysregulation of Neural Progenitors and Birth Defect Formation in Rats

Cortical heterotopias are clusters of ectopic neurons in the brain, and are commonly associated with pharmaceutical resistant epilepsy in patients. We have previously characterized the robust penetrance of a cortical heterotopia in a rat model, induced by thyroid hormone (TH) disruption during gesta...

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發表在:J Endocr Soc
Main Authors: O'Shaughnessy, Katherine, Thomas, Susan, Spring, Stephanie, Ford, Jermaine, Ford, Richard, Gilbert, Mary
格式: Artigo
語言:Inglês
出版: Endocrine Society 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552232/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-045
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