SAT-411 Prepubertal Tonic Gamma-Amino Butyric Acid (GABA) Inhibition Is Upstream of Neurokinin B (NKB), Kisspeptin, and Gonadotropin Releasing Hormone (GnRH) Neuronal Network in Male Rhesus Monkeys

The concept that GnRH release during the prepubertal period is under tonic central inhibition is well established in primates. Although it has been reported that the makorin RING finger protein 3 (MKRN3) gene plays a role in this process (1), neuronal substrates responsible for prepubertal tonic inh...

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Pubblicato in:J Endocr Soc
Autori principali: Garcia, James, Keen, Kim, Anderson, Ryan, Hirshfeld, Brady, Seminara, Stephanie, Terasawa, Ei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2019
Soggetti:
Neuroendocrinology and Pituitary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552168/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-411
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