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Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites
BACKGROUND: Macrophages and their precursors monocytes play a key role in inflammation and chronic inflammatory disorders. Monocyte-to-macrophage differentiation and activation programs are accompanied by significant epigenetic remodeling where DNA methylation associates with cell identity. Here we...
Zapisane w:
| Wydane w: | Epigenetics Chromatin |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6551876/ https://ncbi.nlm.nih.gov/pubmed/31171035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0279-4 |
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