Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats

BACKGROUND: We are investigating a double transgenic rat (dTGR) model, in which rats transgenic for the human angiotensinogen and renin genes are crossed. These rats develop moderately severe hypertension but die of end-organ cardiac and renal damage by week 7. The heart shows necrosis and fibrosis,...

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Main Authors: Theuer, Juergen, Dechend, Ralf, Muller, Dominik N, Park, Joon-Keun, Fiebeler, Anette, Barta, Peter, Ganten, Detlev, Haller, Hermann, Dietz, Rainer, Luft, Friedrich C
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2002
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC65512/
https://ncbi.nlm.nih.gov/pubmed/11835691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-2-3
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